Define Ventures

Define Ventures is a San Francisco-based seed and Series A venture capital firm focused exclusively on healthcare technology, founded by Lynne Chou O'Keefe, who brings over a decade of healthcare investing experience from Kleiner Perkins where she led investments in digital health companies. The firm invests with initial checks from $1 million to $5 million in companies building digital health platforms, value-based care enablement tools, and consumer health technology, with a particular focus on companies improving access to and quality of mental and behavioural health care, primary care, specialty care, and women's and family health services. Define operates from a conviction that healthcare represents the largest sector in the US economy that has been most resistant to technology-driven transformation. Portfolio companies include Brightline, the children's and family behavioral health platform providing virtual therapy and coaching services; Color Health, the population health management and precision medicine company that has expanded into primary care and preventive medicine; Firefly Health, the virtual primary care and health insurance company; and Sword Health, the digital musculoskeletal therapy platform. Beyond its original investments in Brightline, Color Health, Firefly Health, and Sword Health, the portfolio includes additional digital health and healthcare technology companies.